创新药械中心，拥有核酸检测，蛋白研究，细胞研究，中药提取等相关设备500余套，拥有扫描电镜，超速离心机等多种大型仪器设备，致力于打造专业的实验室一体化租赁平台，满足客户各种定制化需求，制定出最佳方案，解决实验室轻资产建设需求，更好满足用户的需求，服务广大生物医药企业和科研工作者，助力生物医药研发。
代表论著：
1.Li Y, Zhang H, Chen C, et al. Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis. Adv Mater. 2022;34(19):e2108476.
2.Liu X, Jin G, Tang Q, et al. Early life Lactobacillus rhamnosus GG colonisation inhibits intestinal tumour formation. Br J Cancer. 2022;126(10):1421-1431.
3.Zhou W, Zhang H, Wang X, et al. Network pharmacology to unveil the mechanism of Moluodan in the treatment of chronic atrophic gastritis. Phytomedicine. 2022;95:153837.
4.Liu H, Yang J, Zhang Y, et al. Psychologic Stress Drives Progression of Malignant Tumors via DRD2/HIF1alpha Signaling. Cancer Res. 2021;81(20):5353-5365.
5.Zhang H, Chang Z, Qin LN, et al. MTA2 triggered R-loop trans-regulates BDH1-mediated beta-hydroxybutyrylation and potentiates propagation of hepatocellular carcinoma stem cells. Signal Transduct Target Ther. 2021;6(1):135.
6.Liu H, Tao H, Wang H, et al. Doxycycline Inhibits Cancer Stem Cell-Like Properties via PAR1/FAK/PI3K/AKT Pathway in Pancreatic Cancer. Front Oncol. 2020;10:619317.
7.Gao WQ, Hu XM, Zhang Q, et al. Downregulation of circFASTKD1 ameliorates myocardial infarction by promoting angiogenesis. Aging (Albany NY). 2020;13(3):3588-3604.
8.Liu H, Qin Y, Li K, et al. Potential type 2 diabetes mellitus drug HMPA promotes short-chain fatty acid production by improving carbon catabolite repression effect of gut microbiota. Br J Pharmacol. 2021;178(4):946-963.
9.Ding XJ, Zhang ZY, Jin J, et al. Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin. Theranostics. 2020;10(24):11110-11126.
10.Zhong W, Sun B, Ruan H, et al. Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function. iScience. 2020;23(9):101464.
11.Wang HG, Yan H, Wang C, et al. circAFF1 Aggravates Vascular Endothelial Cell Dysfunction Mediated by miR-516b/SAV1/YAP1 Axis. Front Physiol. 2020;11:899.
12.Liu HJ, Qin Y, Zhao ZH, et al. Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway. Theranostics. 2020;10(20):9083-9099.
13.Zhong W, Hou H, Liu T, et al. Cartilage Oligomeric Matrix Protein promotes epithelial-mesenchymal transition by interacting with Transgelin in Colorectal Cancer. Theranostics. 2020;10(19):8790-8806.
14.Yang W, Li Z, Qin R, et al. YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA. Front Oncol. 2019;9:1187.
15.Zhang H, Zhong WL, Sun B, et al. Targeted Drug-Loaded Chemical Probe Staining Assay to Predict Therapy Response and Function as an Independent Pathological Marker. iScience. 2019;21:549-561.
16.Zhou B, Zong S, Zhong W, et al. Interaction between laminin-5gamma2 and integrin beta1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins. Oncogene. 2020;39(7):1527-1542.
17.Wang H, Zhang Y, Zhang C, Tong X. Screening prognosis-related genes in glioblastoma by microarray analysis. Anticancer Drugs. 2020;31(2):150-157.
18.Gao W, Zhang X, Yang W, et al. Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells. J Immunother Cancer. 2019;7(1):231.
19.Yang L, Zhang XY, Li K, et al. Protopanaxadiol inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway. Cell Death Dis. 2019;10(9):630.
20.Zhong W, Yang W, Qin Y, et al. 6-Gingerol stabilized the p-VEGFR2/VE-cadherin/beta-catenin/actin complex promotes microvessel normalization and suppresses tumor progression. J Exp Clin Cancer Res. 2019;38(1):285.
21.Wang B, Zhou W, Zhang H, Wang W, Zhang B, Li S: Exploring the effect of Weifuchun capsule on the toll-like receptor pathway mediated HES6 and immune regulation against chronic atrophic gastritis. J Ethnopharmacol 2022:115930.
22.Zhou W, Zhang H, Wang X, Kang J, Guo W, Zhou L, Liu H, Wang M, Jia R, Du X et al: Network pharmacology to unveil the mechanism of Moluodan in the treatment of chronic atrophic gastritis. Phytomedicine 2022, 95:153837.
23.Guo WY,Zhang H , Zhang YY,Wang ShY, Ren J,Jia YQ, Liu R, Zhang B. (2022)Transport mechanism of eurycomanone from Eurycoma longifolia Jack across Caco-2 cells model.Journal of Food Bioactives.17:27-33.
业务合作
津药联合技术服务介绍
/Channel.aspx?channelId=af27fa56-3e9a-47ed-b11c-669ff79cdb04
联系人：吴先生
电 话：15620306200 022-65378061
邮 箱：wuhaidong@tjab.org